DIFFERENTIAL DIAGNOSTICS OF BULLOUS DERMATOSES

Differential diagnostics of bullous dermatoses

Bullous dermatoses are the diseases characterized by vesication and erosion of skin and/or mucos coats, production of autoantibodies against the structural components of Lift Kit epidermis and/or derma.The most frequent diseases of these disorders are pemphigus, bullous pemphigoid, dermatitis herpetiformis, beningn familial chronic pemphigus (Gouge

read more

Intraclade heterogeneity in nitrogen utilization by marine prokaryotes revealed using stable isotope probing coupled with tag sequencing (Tag-SIP)

Nitrogen can greatly influence the structure and productivity of microbial communities through its relative availability and form.However, roles of specific organisms in the uptake of different nitrogen species remain poorly characterized.Most studies seeking to identify agents of assimilation have been correlative, indirectly linking activity meas

read more

Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

Overwhelming lipid peroxidation induces ferroptotic stress and ferroptosis, a non-apoptotic form of regulated cell death that has been implicated in maladaptive renal repair in mice and humans.Using single-cell transcriptomic and mouse CHERRY PLUM genetic approaches, we show that proximal tubular (PT) cells develop a molecularly distinct, pro-infla

read more

Artemisinin resistance-associated markers in Plasmodium falciparum parasites from the China-Myanmar border: predicted structural stability of K13 propeller variants detected in a low-prevalence area.

BACKGROUND:Malaria reduction and future elimination in China is made more difficult by the importation of cases from neighboring endemic countries, particularly Myanmar, Laos, and Vietnam, and increased travel to Africa by Chinese nationals.The increasing prevalence of artemisinin resistant parasites across Southeast Asia highlights the importance

read more